| aaindexextract

## Function

Extract data from AAINDEX

## Description

aaextractindex extracts information from the AAINDEX database for use by pepwindow and pepwindowall

AAINDEX is a database of properties of amino acids. See references [1] [2] [3].

The programs pepwindow and pepwindowall normally use the standard EMBOSS data file 'Enakai.dat' by default, but you can set their '-data' qualifier to use any of the files produced by aaextractindex from the AAINDEX database.

The AAINDEX database file 'aaindex1' can be downloaded from the AAINDEX site: ftp://ftp.genome.ad.jp/pub/db/genomenet/aaindex/aaindex1

## Usage

Here is a sample session with aaindexextract:

    % aaindexextract
    Extract data from AAINDEX
    Full pathname of file aaindex1: ~/aaindex1

## Command line arguments

       Mandatory qualifiers:
      [-inf]               infile     Full pathname of file aaindex1

       Optional qualifiers: (none)
       Advanced qualifiers: (none)
       Associated qualifiers: (none)
       General qualifiers:
       -auto                boolean    Turn off prompts
       -stdout              boolean    Write standard output
       -filter              boolean    Read standard input, write standard output
       -options             boolean    Prompt for required and optional values
       -debug               boolean    Write debug output to program.dbg
       -acdlog              boolean    Write ACD processing log to program.acdlog
       -acdpretty           boolean    Rewrite ACD file as program.acdpretty
       -acdtable            boolean    Write HTML table of options
       -verbose             boolean    Report some/full command line options
       -help                boolean    Report command line options. More
                                      information on associated and general
                                      qualifiers can be found with -help -verbose
       -warning             boolean    Report warnings
       -error               boolean    Report errors
       -fatal               boolean    Report fatal errors
       -die                 boolean    Report deaths

Mandatory qualifiers | Allowed values | Default
--- | --- | ---
[-inf] (Parameter 1) | Full pathname of file aaindex1 | Input file | Required
Optional qualifiers | Allowed values | Default
(none)
Advanced qualifiers | Allowed values | Default
(none)

## Input file format

The AAINDEX database file 'aaindex1' can be downloaded from the AAINDEX site: ftp://ftp.genome.ad.jp/pub/db/genomenet/aaindex/

## Output file format

One file for every entry in the AAINDEX database is created in the EMBOSS standard 'data/AAINDEX' directory. For example, the file 'cham830102':

    H CHAM830102
    D A parameter defined from the residuals obtained from the best correlation
      of the Chou-Fasman parameter of beta-sheet (Charton-Charton, 1983)
    R LIT:0907093b PMID:6876837
    A Charton, M. and Charton, B.
    T The dependence of the Chou-Fasman parameters on amino acid side chain
      structure
    J J. Theor. Biol. 111, 447-450 (1983)
    * (Pro !)
    C
    I   A/L    R/K    N/M    D/F    C/P    Q/S    E/T    G/W    H/Y    I/V
       -0.118  0.124  0.289  0.048  0.083 -0.105 -0.245  0.104  0.138  0.230
       -0.052  0.032 -0.258  0.015  0.     0.225  0.166  0.158  0.094  0.513
    //

## Data files

None.

## Notes

If aaindexextract tries to write the data to an unexpected location you can explicitly set the location of the EMBOSS data directory by putting the line:

ENV EMBOSS_DATA /path/to/the/EMBOSS/data/directory
in the EMBOSS emboss.default file.

(Where '/path/to/the/EMBOSS/data/directory' is the location of your EMBOSS data as unpacked from the distribution file.)

## References

1. Nakai, K., Kidera, A., and Kanehisa, M.; Cluster analysis of amino acid indices for prediction of protein structure and function. Protein Eng. 2, 93-100 (1988). [UI:89221001]
2. Tomii, K. and Kanehisa, M.; Analysis of amino acid indices and mutation matrices for sequence comparison and structure prediction of proteins. Protein Eng. 9, 27-36 (1996). [UI:96272030]
3. Kawashima, S., Ogata, H., and Kanehisa, M.; AAindex: amino acid index database. Nucleic Acids Res. 27, 368-369 (1999). [UI:99063742]

## Warnings

None.

## Diagnostic Error Messages

None.

## Exit status

It always exits with status 0.

## Known bugs

None.

## See also

Program name | Description
--- | ---
cutgextract | Extract data from CUTG
printsextract | Extract data from PRINTS
prosextract | Builds the PROSITE motif database for patmatmotifs to search
rebaseextract | Extract data from REBASE
tfextract | Extract data from TRANSFAC

The programs pepwindow and pepwindowall normally use the standard EMBOSS data file 'Enakai.dat' by default, but you can set their '-data' qualifier to use any of the files produced by aaextractindex.

## Author(s)

Peter Rice (pmr © ebi.ac.uk)
Informatics Division, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK

## History

Written (25 June 2002) - Peter Rice

## Target users

This program is intended to be used by administrators responsible for software and database installation and maintenance.

## Comments